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Vaccine efficacy for Pfizer shows a greater decline in men and those with immunosuppression over a period of 6 months. Vaccine efficacy also declines more rapidly in those above 65 years of age.

Vaccine efficacy for Pfizer shows a greater decline in men and those with immunosuppression over a period of 6 months. Vaccine efficacy also declines more rapidly in those above 65 years of age.

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4 Comments

  1. Is this study just saying that the immune system of immunosuppressed people is less active? And that the immune system produces less antibodies for something it hasn’t encountered in months? Because both of those are just basic information about how the immune system works. Or is it claiming any sort of specific effect of the Pfizer vaccine or vaccines in general, because the abstract doesn’t make that clear?

  2. Would be great to see data on how this impacts outcomes of breakthrough infection… or to see how antibody tigers respond to infection or re-infection and outcomes of people infected (or re-infected) 6 and 12 and 18 months post vaccination (or initial infection)

  3. I’m really tired of the phrase “vaccine efficacy”. Antibody titres aren’t the end all be all for preventing death. The memory arm of the immune system still exists and protects folks from death. It’s energetically taxing to produce antibodies all the time for every pathogen you’ve ever encountered, and sterilizing immunity is rare.

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